dry skin, deep lines, loss of bounce? meet your clean, clinically active solution

Powered by dual-action Matrixyl® and Proteasyl® peptides, this rich cream delivers deep hydration while boosting collagen and firmness for skin that looks plumper and years younger.
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Any Of These Skin Frustrations Sound Familiar?

Deep Wrinkles 

Lines that seem to get deeper every year, no matter what products you try.

Loss of Elasticity 

Skin that's lost its bounce and doesn't spring back like it used to

Chronic Dryness 

Moisturizers that wear off in hours, leaving skin tight and parched.

Dull, Tired Look 

That youthful glow has faded, replaced by lackluster, aging skin.

Not All Peptides Are Created Equal

Here's the truth most skincare brands won't tell you: cheap peptides only work on the surface. They provide temporary hydration but do nothing for the deeper structural damage causing your wrinkles.

 

That's why we use Matrixyl® and Proteasyl® clinically proven peptides that work at the cellular level to rebuild collagen, restore elasticity, and create lasting transformation.

 

The difference? Results you can actually see, not just feel for a few hours.

Peptide Quality Matters

  • Good: Matrixyl® & Proteasyl®

    Works deep within skin, rebuilds collagen, lasting results

  • Cheap Surface Peptides 

    Only temporary hydration, no structural repair

  • Clinically Proven Technology

    Backed by studies, measurable wrinkle reduction

  • Marketing Claims Only 

    Feels nice but no real anti-aging benefit

The Culprit? Declining Collagen Production

Starting in your mid-20s, your skin naturally begins producing less collagen—the essential protein that helps keep skin firm, smooth, and resilient. As collagen levels gradually decline over time, skin can begin to lose some of its bounce and elasticity. By the time you reach your 50s, nearly half of your skin’s collagen has naturally diminished.

 

Daily sun exposure, environmental stressors, and harsh ingredients found in many skincare products can accelerate that decline even more. The visible result? Skin that can feel drier, look less radiant, and show more noticeable lines and wrinkles than it used to.

 

Here’s the encouraging part: with the right peptide technology, you can help support your skin’s natural collagen-building process. Supreme Polypeptide Cream uses advanced peptides to help visibly smooth, deeply hydrate, and restore the look of firmer, more supple skin—naturally and beautifully over time.

The Science-Backed Duo That Transforms Skin

We didn't settle for just one peptide. Our formula combines two powerhouse ingredients that work together for visible, lasting transformation.

Matrixyl® 

Works deep within the skin to boost collagen production, smooth wrinkles, and restore elasticity from the inside out.

Proteasyl® TP Pea Peptide 

Strengthens the skin barrier and enhances firmness for a naturally youthful, radiant glow that lasts.

Supreme Polypeptide Cream:Your Luxury Treatment

  A rich, nourishing cream that delivers real results—not just promises.

clean vs. conventional: choose wisely

See why MyCHELLE stands apart from typical anti-aging creams.

supreme polypeptide cream

Typical Creams

what's inside

Dual Peptide Technology                                    

Clinically Proven Ingredients                               

Cruelty-Free & Vegetarian                                   

Free of Parabens & Sulfates                               

Unscented / No Artificial Fragrance                     

No Silicones or Petroleum                                   
A jar of Supreme Polypeptide Cream Unscented by MyCHELLE. Has a white label that includes purple graphics.
MyChelle Dermaceuticals Ageless Supreme Polypeptide Cream jar with labeled ingredients on a beige background
Woman's face with skincare benefits listed.
Beige cream with text listing ingredients it is 'Made Without' on a beige background
Five-star rating with a positive review on a gradient background

ANTI-AGING SKINCARE

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Supreme Polypeptide Cream Unscented

When your skin craves deep hydration that actually lasts, and you want visible plumping and firming—not just temporary moisture—Supreme Polypeptide Cream delivers what basic moisturizers can't.

MATRIXYL® 

PROTEASYL® 

CRUELTY-FREE 

UNSCENTED

Use Code SUPREME20 at Checkout for 20% Off

Retail Price: $59.99

Use Code SUPREME20 at Checkout

100% Satisfaction Guarantee

Why You Will Love It

Dual Peptides

Matrixyl® + Proteasyl®

Cruelty-Free

Never tested on animals

Clean Formula 

No bad stuff inside

 Unscented

No fragrance, no irritation

Calm and Kind

Soft on sensitive skin

Real Women, Real Results

See what our customers are saying about Supreme Polypeptide Cream.

How To Use

Experience our prestigious after-sales service.

Cleanse & Prep 

 Start with clean skin. Apply any serums first (we recommend Peptide⁺ Serum for maximum results).

Apply Cream 

Take a small amount and gently massage into face and neck using upward strokes.

Use Daily 

Apply morning and evening for best results. Pairs beautifully with the entire Ageless line.

Pair With Peptide⁺ Serum for Even Greater Results

Layer the serum under this cream for the ultimate anti-aging routine. The serum delivers active peptides deep into skin, while the cream locks in moisture and provides additional firming benefits.

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Frequently Asked Questions

What makes this cream different from other moisturizers? 

Supreme Polypeptide Cream uses dual-action Matrixyl® and Proteasyl® TP Pea Peptide—clinically proven ingredients that work at the cellular level. Unlike cheap peptides that only provide surface hydration, our formula rebuilds collagen and restores elasticity for lasting, visible transformation.

What are Matrixyl® and Proteasyl®? 

Matrixyl® is a patented peptide that signals your skin to produce more collagen, effectively smoothing wrinkles from within. Proteasyl® TP Pea Peptide strengthens the skin barrier and enhances firmness. Together, they are a winning combination.

How soon will I see results? 

Many users notice improved hydration immediately and see visible plumping within 1-2 weeks. More significant anti-aging benefits like reduced wrinkles and improved firmness typically become visible after 4-8 weeks of consistent use.

Is it suitable for sensitive skin? 

Yes! Our unscented formula is the perfect choice for sensitive skin. It's free of artificial fragrances, parabens, sulfates, silicones, and other common irritants. The gentle formula is cruelty-free and vegetarian.

Can I use this around my eyes? 

Yes, the gentle formula is safe for the eye area. Many customers specifically love the results around their eyes. For targeted eye treatment, you can also pair it with our dedicated eye cream.

Should I use this with the Peptide⁺ Serum? 

Absolutely! For best results, apply Peptide⁺ Serum first, then follow with Supreme Polypeptide Cream. The serum helps deliver concentrated peptides deep into skin, while the cream locks in moisture and helps provide additional firming benefits.

Experience the Difference Real Peptides Make

Join the thousands of women who've discovered the MyChelle difference.

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