A jar of Supreme Polypeptide Cream Unscented by MyCHELLE. Has a white label that includes purple graphics.
MyChelle Dermaceuticals Ageless Supreme Polypeptide Cream jar with labeled ingredients on a beige background
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An informational graphic titled 'SKIN AGING' over a close-up yellow-orange leaf texture with a translucent droplet on the right. Text outlines skin changes by decade from 20's to 60's.
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Visibly firms and smooths skin

Defends against environmental damage

Boosts skin's elasticity and resilience

Supreme Polypeptide Lifting Cream Unscented

$59.00
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Title

  • DETAILS

  • HOW TO USE 

  • INGREDIENTS

Multi-Peptide Complex supports skin’s natural collagen to visibly firm and smooth fine lines.

Matrixyl ® synthe’6™ (Palmitoyl Tripeptide-38) clinically shown to reduce wrinkle depth and improve skin tone and texture.

Argan Plant Stem Cells help improve skin resilience and promote a more lifted appearance.

Start with clean, dry skin. For best results, apply after gentle cleansing.

Use morning and evening as the final step in your skincare routine (before SPF in the AM).

Gently massage a small amount onto face, neck, and décolleté in upward strokes.

Pro Tip: layer over your favorite MyCHELLE serum, such as the Perfect C Vitamin C Serum.
Aqua (Water), Helianthus Annuus (Sunflower) Seed Oil, Glycerin, Caprylic/Capric Triglyceride, Squalane, Cetearyl Alcohol, Cetearyl Olivate, Ribes Nigrum (Black Currant) Seed Oil, Butyrospermum Parkii (Shea) Butter, Mangifera Indica (Mango) Seed Butter, C18-36 Acid Triglyceride, Rosa Canina (Rosehip) Seed Oil*, Sorbitan Olivate, Simmondsia Chinensis (Jojoba) Seed Oil, Palmitoyl Tripeptide-5, Palmitoyl Tripeptide-38, Pisum Sativum (Pea) Extract, Hyaluronic Acid, Sphingolipids, Polygonum Cuspidatum (Giant Knotweed) Extract, Astaxanthin, Tocotrienols, Tocopherol (D), Crocus Chrysanthus Bulb Extract, Camellia Sinensis (Green Tea) Leaf Extract, Glucosamine HCl (D), Hydrolyzed Rice Protein, Honey (Mel), Hamamelis Virginiana (Witch Hazel) Water, Cassia Angustifolia Seed Polysaccharide, Phospholipids, Elaeis Guineensis (Palm) Oil, Totarol, Xanthan Gum, Hydroxypropyl Cyclodextrin, Acacia Senegal Gum, Phenethyl Alcohol, Caprylyl Glycol, Potassium Sorbate, Alcohol Denat., Alcohol, Trisodium Ethylenediamine Disuccinate, Citric Acid, Sodium Hydroxide, Polysorbate 60, Polysorbate 20
*Organic

Full disclosure ingredients according to PCPC standards

Proven. Trusted. Awarded

Reveal firmer, smoother, more youthful skin with the MyCHELLE Ageless Collection — a curated blend of multi-peptides, antioxidants, and hydrating botanicals. Each clean, clinically inspired formula targets fine lines, improves elasticity, and restores radiance—without compromise.

Explore the AGELESS Collection

Why Our Supreme Polypeptide Cream

Is Different

Most anti-aging creams promise results. MyCHELLE delivers them — without compromising on clean ingredients, safety, or performance.
No fillers. No fluff. Just clinically advanced age-defying hydration.

Supreme Polypeptide Cream

Other Anti-Aging Creams

Multi-peptide technology supports elasticity

Often rely on single peptides or generic extracts

Formulated with peptides like Matrixyl ® synthe’6

Low quantity or low-potency peptides

No artificial fragrance

Synthetic fragrance or oils that may irritate

Free from silicones, petroleum, and parabens

Frequently include harsh preservatives

Full transparency of every ingredient

Vague labeling or proprietary blends
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Ask us anything

What does the Supreme Polypeptide Cream do for my skin?

It helps improve skin firmness, reduce the appearance of fine lines and wrinkles, and boost elasticity. Formulated with multi-peptide complexes and antioxidants, it supports a more youthful, resilient complexion.

What are peptides, and why are they important?

Peptides are short chains of amino acids that act as building blocks for proteins like collagen and elastin. They help signal your skin to repair and strengthen itself, making them essential for anti-aging and skin rejuvenation.
 

Can I use this cream with other serums or treatments?

Absolutely. It works well layered over serums (like our Peptide Plus Anti-Wrinkle Serum) and under SPF. Apply serums first, then follow with the Supreme Polypeptide Cream.

How often should I use it?

For best results, use twice daily—morning and night—as the final step in your skincare routine before sunscreen or makeup.

When should I start to see results?

Most users notice improved hydration and smoother texture within the first few weeks. Visible firmness and wrinkle reduction typically appear with consistent use over 4–6 weeks.
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