Fragrance-Free Peptide Moisturizer
Visible plumping for sensitive, aging skin.
A rich-but-not-greasy peptide cream that deeply hydrates, softens the look of fine lines, and leaves skin feeling smoother and firmer—morning and night.
- Deep, lasting hydration for dry or depleted-feeling skin
- Helps visibly plump and smooth the look of fine lines
- Fragrance-free care designed with sensitive skin in mind
Apply to face and neck twice daily. Follow with SPF in the morning. Packaging may display the shorter name “Supreme Polypeptide Cream Unscented.”
“It is not only moisturizing, it is plumping which helps with the lines and wrinkles.”
- 124 Reviews4.8 out of 5 average
- Fragrance-FreeNo artificial fragrance
- AM + PMOne dependable cream
- VeganCruelty-free formula
Gentle should still feel effective
Sensitive skin should not have to settle for basic hydration.
“Whenever I run out and don't use it for a while, I really notice the difference in my skin.”
Supreme Polypeptide Cream pairs nourishing moisture with a multi-peptide formula, giving dry, sensitive, aging skin the comfort it wants and the visible smoothing it is looking for.
That combination is why customers repeatedly describe it as their favorite, their go-to, and the moisturizer they have used for years.
What customers come back for
Hydration you can feel. A plumper look you notice.
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Deeply hydrates dry, mature-feeling skin
Helps replenish moisture so skin feels softer, more supple, and comfortable through the day or night.
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Helps visibly plump and smooth
Peptide-powered care supports a fresher, smoother appearance and helps soften the look of fine lines with consistent use.
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Rich nourishment without the greasy finish
A comforting cream texture designed to layer over serum and fit easily into both morning and evening routines.
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Fragrance-free care for sensitive skin
No artificial fragrance—so the formula can focus on moisture, peptides, and a skin-comforting daily experience.
The reason to believe
More than moisture: a multi-peptide approach.
The outcome comes first. The peptides explain how this moisturizer supports a smoother, firmer-looking complexion.
- Multi-Peptide ComplexA focused blend selected to support smoother, firmer-looking skin.
- Matrixyl® synthe'6™A peptide technology used to support smoother-looking skin and soften the appearance of lines.
- Argan Plant Stem CellsIncluded to support a more resilient-looking complexion.
- Pea Peptide ExtractSupports the appearance of firmness and texture.
Ingredient benefits describe cosmetic appearance support. Individual results vary.
One cream, twice daily
Easy enough to become the step you never skip.
A small amount goes a long way. Layer from thinnest to thickest and allow serums to absorb before applying the cream.
Hydrate and protect
Apply to clean skin after serum, then finish with daily SPF.
Nourish and replenish
Massage a small amount over face and neck as the final step in your evening routine.
Customer reviews for Supreme Polypeptide Lifting Cream Unscented
What verified buyers say
“My face cannot go without the supreme polypeptide unscented cream. I've been using it for well over a decade...”Verified Buyer · Supreme Polypeptide Lifting Cream Unscented
“Supreme Polypeptide Cream Unscented is perfect for my sensitive older skin. Brightens, moisturizes and reduces appearance of wrinkles.”Verified Buyer
“This is my favorite moisturizer of all time. It deeply moisturizes my skin without ever making me feel oily. I love that it is unscented.”Verified Buyer
“Keeps my skin hydrated and looks and feels smooth and soft.”Verified Buyer
“It keeps my skin from being dry but it’s never greasy. It sinks right into my skin and make it dewy.”Verified Buyer
Track your progress
See your routine in consistent conditions.
Use a simple photo-and-notes check-in to follow hydration, comfort, texture and appearance over time.
Optional personal progress guide
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Set a clean baseline
Before you begin, take front and side photos in natural light with clean skin, no makeup and a neutral expression.
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Repeat the same setup
If you choose to check at 2, 4 and 8 weeks, keep the camera, distance, angle, light, time of day and expression as consistent as possible.
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Track what you can feel
Note twice-daily consistency along with hydration, comfort, texture, finish and how the formula layers with the rest of your routine.
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Compare only unedited images
Review the photos with your notes on softness, the look of plumpness and fine lines, and overall comfort. Individual experiences vary.
This guide does not ask you to upload or share photographs. Keep them on your own device and use them only in the way you choose. Individual experiences vary.
Clean, considered care
What is left out matters, too.
Fragrance-free, vegan, cruelty-free, and formulated without common ingredients MyCHELLE customers choose to avoid.
- Artificial Fragrance
- Artificial Colors
- Parabens
- Petroleum
- Phthalates
- Silicones
- Sulfates
- Ureas
Questions before you start
A better routine starts with clear expectations.
Is it suitable for sensitive skin?
The fragrance-free formula is designed with sensitive skin in mind. Because every complexion is different, patch test first if your skin is highly reactive.
Does fragrance-free mean completely odorless?
Fragrance-free means no artificial fragrance is added. The raw ingredients may have a faint natural aroma that can vary slightly and usually dissipates after application.
Will it feel heavy or pill under other products?
Use a small amount and layer from thinnest to thickest. Allow serum to absorb before applying the cream. In the morning, finish with SPF.
When should I expect results?
Hydration and softness may be noticeable quickly. Visible plumping, smoothing, and firmness vary by person and are best judged with consistent twice-daily use. Individual results vary.
Can I use it with retinol, vitamin C, or other serums?
Yes. It can be used as the moisturizing step after your serum or treatment. If your routine causes irritation, reduce active frequency and keep the rest of the routine simple.
How do I use it?
Apply a small amount to clean face and neck morning and evening. Massage gently in upward motions. Follow with sun protection every morning.
Your AM + PM peptide cream
Hydrate. Plump. Keep sensitive skin comfortable.
Supreme Polypeptide Lifting Cream Unscented
- Fragrance-free multi-peptide moisturizer
- For all skin types, especially sensitive and dry
- Vegan, cruelty-free, and recyclable packaging
One-time price shown. Subscription options and current availability appear on the product page.